The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2002

Filed:

Mar. 02, 2000
Applicant:
Inventor:

Mazin Nicola, Worthing, GB;

Assignee:

Advanced Phytonic Limited, West Yorkshire, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 3/706 ; C12P 3/700 ; C12P 1/00 ; C12P 3/502 ;
U.S. Cl.
CPC ...
C12P 3/706 ; C12P 3/700 ; C12P 1/00 ; C12P 3/502 ;
Abstract

A first compound is converted to a second compound enzymatically in a solvent mixture containing water and a fluorinated, non-chlorinated alkane, alkene, or alkyne having up to 4 carbon atoms. Lactams, for example 6-aminopenicillanic acid (6-APA), may be prepared by enzymatic conversion of a first compound, for example penicillin-G, in a solvent mixture comprising water and a non-aqueous organic solvent, for example 1,1,1, 2-tetrafluoroethane. The 6-APA can be caused to precipitate, isolated by filtration and optionally derivatized to produce a desired compound. A by-product of the enzymatic conversion, for example phenylacetic acid, can be isolated by solvent extraction, suitably using a solvent which also comprises 1, 1, 1, 2-tetrafluoroethane.


Find Patent Forward Citations

Nicola, Mazin. (2002). Enzymatic conversion in a solvent mixture containing water and flourinated, non-chlorinated solvent (U.S. Patent No. 6383772). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6383772

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