The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2002
Filed:
Jul. 15, 1999
Applicant:
Inventors:
Reinhard Kurth, Dreieich, DE;
Michael Baier, Frankfurt, DE;
Karin Metzner, Frankfurt, DE;
Albrecht Werner, Frankfurt, DE;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/70 ; C12Q 3/00 ; C12Q 1/00 ; G01N 3/3567 ; C12P 2/102 ;
U.S. Cl.
CPC ...
C12Q 1/70 ; C12Q 3/00 ; C12Q 1/00 ; G01N 3/3567 ; C12P 2/102 ;
Abstract
The present invention is directed to an Immunodeficiency-virus Suppressing Lymphokine (ISL) produced by stimulated CD8+ PBMC, cloning and isolation of nucleic acid molecules for eukaryotic ISL, and methods of treating viral infections with ISL. ISL is able to suppress the replication of viruses, especially retroviruses, in vitro and in vivo. More, specifically, a method is described for detecting a compound capable of inducing the expression of ISL by measuring the presence of ISL and the ability of ISL to inhibit HIV transcription.