The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2002
Filed:
Feb. 16, 1999
Applicant:
Inventors:
Hartmut Beug, Vienna, AT;
Martin Oft, Vienna, AT;
Ernst Reichmann, Epalinges, CH;
Karl-Heinz Heider, Stockerau, AT;
Assignee:
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; G01N 3/353 ; G01N 3/3567 ; C12N 1/500 ; C12N 1/509 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; G01N 3/353 ; G01N 3/3567 ; C12N 1/500 ; C12N 1/509 ;
Abstract
Pharmaceutical compositions containing as active compound a substance which inhibits the activity of TGF&bgr; on tumour cells of epithelial origin, for the treatment of epithelial, invasive tumour diseases which are characterized by a reversible transition of the cells from an epithelial, non-invasive state into a fibroblastoid, invasive state. The pharmaceutical composition contains a TGF&bgr; inhibitor, preferably combined with an Ras inhibitor. Process for screening substances for the treatment of epithelial, invasive tumour diseases.