The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2002

Filed:

Dec. 26, 2000
Applicant:
Inventors:

Tomoaki Hirayama, Tokyo, JP;

Hiroshi Murata, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61K 9/20 ; A61K 9/48 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61K 9/20 ; A61K 9/48 ;
Abstract

A crystalline bulk powder of N-(1-((2,4-diamino-6-pteridinyl)methyl)-3,4-dihydro-2H-1,4-benzothiazine-7-carbonyl)L-&agr;-aminoadipic acid is treated by using an impact grinding method or a jet mill grinding method to give a finely ground powder. Solid oral preparations containing the thus obtained finely ground powder as the active ingredient can quickly release the active ingredient and high content uniformity can be ensured without adversely affecting the stability.


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