The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2002

Filed:

Dec. 17, 1998
Applicant:
Inventors:

Lothar W. Kleiner, Los Altos, CA (US);

Robert M. Gale, Los Altos, CA (US);

Randall G. Berggren, Livermore, CA (US);

Gilbert T. Tong, Union City, CA (US);

Guohua Chen, Sunnyvale, CA (US);

Keith E. Dionne, Cambridge, MA (US);

Paul R. Houston, Hayward, CA (US);

Assignee:

ALZA Corporation, Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 ; A61K 9/24 ;
U.S. Cl.
CPC ...
A61K 9/70 ; A61K 9/24 ;
Abstract

This invention provides rate controlling membranes for controlled drug delivery devices that are stable over time and exhibit more predictable and consistent membrane functionality. According to another aspect, the membranes have enhanced permeability. According to the invention, the rate controlling membrane of a controlled drug delivery device is subjected to a pre-treatment annealing process wherein it is subjected to an elevated temperature for a predetermined time period and subsequently cooled to ambient conditions before incorporation into a controlled drug delivery device.


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