The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2002

Filed:

May. 16, 2000
Applicant:
Inventors:

Karen Jane Barnes, Chesham, GB;

Gary Robert Bower, Aylesbury, GB;

Alan Michael Forster, High Wycombe, GB;

Peter Knox, Chalfont St Giles, GB;

Marivi Mendizabal, London, GB;

Anthony Eamon Storey, Amersham, GB;

Assignee:

Amersham International PLC, Little Chalfont Bucks, US;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 5/100 ; A61M 3/614 ;
U.S. Cl.
CPC ...
A61K 5/100 ; A61M 3/614 ;
Abstract

A human leucocyte elastase (HLE) inhibitor labelled with a detector moiety where the inhibitor is synthetic and has a molecular weight of less than 2000, is useful for the diagnostic imaging of sites of inflammation of infection in vivo, for labelling leucocytes in vitro, or for radiotherapy of rthritis. The HLE inhibitor is preferably a &bgr;-lactam or an azetidinone.


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