The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2002
Filed:
Mar. 01, 2000
Applicant:
Inventors:
Lars Karlsson, La Jolla, CA (US);
Wai-Ping Leung, San Diego, CA (US);
Per A. Peterson, Rancho Santa Fe, CA (US);
Christopher Alfonso, San Diego, CA (US);
Assignee:
Ortho McNeil Pharmaceutical, Inc., Raritan, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 6/700 ; A01K 6/7027 ; C12N 1/500 ; C12P 2/100 ;
U.S. Cl.
CPC ...
A01K 6/700 ; A01K 6/7027 ; C12N 1/500 ; C12P 2/100 ;
Abstract
A transgenic animal with alterations in an H2-O gene is prepared by introduction of an altered H2-O gene into a host animal. The resulting transgenic animals produce a substantially greater frequency of high affinity antibodies compared to H2-O wild type animals. A method for the production of high affinity antibodies is disclosed.