The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 16, 2002

Filed:

Jul. 07, 2000
Applicant:
Inventors:

James Gregory Bentsen, North Saint Paul, MN (US);

Christopher Allen Mickelson, Saint Paul, MN (US);

Orlin Bruce Knudson, Vadnais Heights, MN (US);

Kevin Michael Lewandowski, Inver Grove Heights, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07G 1/100 ;
U.S. Cl.
CPC ...
C07G 1/100 ;
Abstract

Disclosed are novel coumarin based fluorogenic compounds useful in assaying for biological activity. Specifically, these fluorogenic compounds exhibit fluorescence at particular wavelengths when cleaved by target enzymes. Preferred compounds include sugar and peptide derivatives of umbelliferone derivatives bearing a heterocyclic five membered ring at the 3-position. These compounds can be used for rapidly detecting food pathogens and for determining sterilization effectiveness. The compounds may also be used in a form bounded to a polymeric support or to a biomolecule or macromolecule.


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