The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2002
Filed:
Dec. 08, 1999
Pauline L. Martin, Boston, MA (US);
Donald A. McAfee, Richmond, VA (US);
Discovery Therapeutics, Inc., Richmond, VA (US);
Abstract
In the present invention, a method is provided which reduces or prevents restenosis following revascularization procedures. It has now been found that selective stimulation of adenosine A receptors can reduce or prevent such restenosis. This method may be achieved either by: (a) the administration of selective adenosine A receptor agonists, (b) the administration of a selective adenosine A antagonist in combination with either a selective adenosine A receptor agonist or a non-selective adenosine agonist, or (c) the administration of a selective adenosine A antagonist in order to block adenosine A receptor activation by endogenously-released adenosine. The present invention is also directed to an improved surgical procedure that relies upon selective stimulation of adenosine A receptors.