The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 2002
Filed:
Nov. 12, 1999
Applicant:
Inventors:
Jim Hu, East York, CA;
Yu-Hua Chow, North York, CA;
Hugh O'Brodovich, Oakville, CA;
Lap-Chee Tsui, Etobicoke, CA;
Assignee:
HSC Research and Development Limited Partnership, Toronto, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/563 ; C12N 1/500 ; A01N 6/300 ; A01N 4/304 ; A61K 4/800 ;
U.S. Cl.
CPC ...
C12N 1/563 ; C12N 1/500 ; A01N 6/300 ; A01N 4/304 ; A61K 4/800 ;
Abstract
The invention consists of episomal expression cassettes for expression of a transgene in gene therapy. The expression cassettes consist of regulatory elements of the human cytokeratin gene and a transgene. The invention also includes of liposomes for transfection of epithelial tissue with the cassettes in treatment of cystic fibrosis, emphysema, cancers of epithelial origin arising in the lung or other organs.