The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2002
Filed:
Jun. 12, 2000
James K. Kroeger, Albuquerque, NM (US);
Alan J. Leszinske, Albuquerque, NM (US);
TecMed, Incorporated, Albuquerque, NM (US);
Abstract
A polarimeter adapted for measurement of the concentration of glucose in a sample includes a laser beam passing through a first polarizer and an optical modulator and split into a measurement beam passing through a FIRST ANALYZER to a first detector coupled to a first amplifier and a reference beam passing through a SECOND ANALYZER to a second detector coupled to a second amplifier. Identical multiple filtering and summing operations are performed on outputs of the first and second amplifiers to produce a first &PSgr; /2 signal and a first 2&bgr;&PSgr; signal in response to the measurement beam and a second &PSgr; /2 signal and a second 2&bgr;&PSgr; signal in response to the reference beam. The measurement beam is stabilized by comparing the second &PSgr; /2 signal to a first reference signal to produce a first error signal and comparing the second 2&bgr;&PSgr; signal to a second reference signal to produce a second error signal. The first error signal is multiplied by a modulation signal to produce a modulation feedback signal and adding it to the second error signal to produce a combined modulation and zeroing feedback signal which drives the optical modulator so as to minimize the first and second error signals. First and second values of &bgr; are computed from the first &PSgr; /2 signal and the first 2&bgr;&PSgr; signal without and with the sample in the path of the measurement beam, and the difference is converted to a value of glucose concentration in the sample.