The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2002
Filed:
Mar. 28, 2001
Applicant:
Inventors:
Jorge A. Piedrahita, College Station, TX (US);
Fuller W. Bazer, College Station, TX (US);
Assignee:
Texas A&M University System, College Station, TX (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/585 ; C12N 1/589 ; C12N 1/590 ; C12N 5/06 ; C12N 5/10 ;
U.S. Cl.
CPC ...
C12N 1/585 ; C12N 1/589 ; C12N 1/590 ; C12N 5/06 ; C12N 5/10 ;
Abstract
Disclosed are methods for the isolation of primordial germ cells, culturing these cells to produce primordial germ cell-derived cell lines, methods for transforming both the primordial germ cells and the cultured cell lines, and using these transformed cells and cell lines to generate transgenic animals. The efficiency at which transgenic animals are generated by the present invention is greatly increased, thereby allowing the use of homologous recombination in producing transgenic non-rodent animal species.