The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2002
Filed:
Mar. 04, 1999
Stephen Thomas Davis, Durham, NC (US);
Scott Howard Dickerson, Chapel Hill, NC (US);
Philip Anthony Harris, Raleigh, NC (US);
Robert Neil Hunter, III, Raleigh, NC (US);
Lee Frederick Kuyper, Durham, NC (US);
Karen Elizabeth Lackey, Hillsborough, NC (US);
Michael Joseph Luzzio, Durham, NC (US);
James Marvin Veal, Cary, NC (US);
Duncan Herrick Walker, Summit, NJ (US);
SmithKline Beecham Corporation, Philadelphia, PA (US);
Abstract
The present invention relates generally to novel substituted oxindole compounds and compositions. Such compounds and compositions have utility as pharmacological agents in treating diseases or conditions alleviated by the inhibition or antagonism of protein kinase activated signalling pathways. In particular, the present invention relates to a series of substituted oxindole compounds, which exhibit protein tyrosine kinase and protein serine/threonine kinase inhibition, and which are useful in inhibiting tumor growth via inhibition of such kinases as well as protecting a patient undergoing chemotherapy from chemotherapy induced alopecia.