The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2002
Filed:
Mar. 23, 2000
Applicant:
Inventors:
Gabriel O. Reznik, Boston, MA (US);
Takeshi Sano, Needham, MA (US);
Sandor Vajda, Medfield, MA (US);
Cassandra Smith, Boston, MA (US);
Charles Cantor, Del Mar, CA (US);
Assignee:
The Trustees of Boston University, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; C07K 1/400 ; C07H 2/104 ;
U.S. Cl.
CPC ...
G01N 3/353 ; C07K 1/400 ; C07H 2/104 ;
Abstract
Compounds and methods are described for producing streptavidin mutants with changed affinities. In particular, modifications to the sequence of the natural streptavidin gene is described to create amino acid substitutions resulting in greater affinity for biotin substitutes than for biotin.