The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2002
Filed:
Oct. 26, 1999
Applicant:
Inventors:
Kevin R. McIntosh, Ellicott City, MD (US);
Joseph D. Mosca, Ellicott City, MD (US);
Elena N. Klyushnenkova, Baltimore, MD (US);
Assignee:
Osiris Therapeutics, Inc., Baltimore, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 6/300 ; A61K 3/512 ; A61K 3/528 ; C12N 5/08 ;
U.S. Cl.
CPC ...
A01N 6/300 ; A61K 3/512 ; A61K 3/528 ; C12N 5/08 ;
Abstract
A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of mesenchymal stem cells effective to reduce or inhibit host rejection of the transplant. The mesenchymal stem cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with mesenchymal stem cells.