Bioactivating substance

Abstract

A highly active bioactivating substance which exhibits suppressing action on histamine liberation and inhibition of hyaluronidase activity may be obtained by adding a silicate to an extracted substance from tissues activated by adding internal or external stressors to animals or animal tissues such as infecting with poxvirus. The highly active bioactivating substance may also be obtained by performing a special extraction to effect a high content of silicic acid in the extracted substance from the activated tissues. The bioactivating substance may be in the form of a powder and may have a silicon component content which is more than 20 &mgr;g, for example greater 22 &mgr;g, preferably greater than 25 &mgr;g, calculated as silicon per mg of dried substance. The powder may be obtained by admixing an extract from activated tissue, which extract contains at least one silicon component, with at least one additional silicon component to obtain a mixture, and drying the mixture to obtain a powder which exhibits positive color reactions to amino acid (by a ninhydrin reaction), saccharide (by an orcinol-iron (III) chloride-hydrochloric acid method), phosphorus (by a molybdenum blue method) and silicic acid (by a molybdenum blue method), and negative qualitative reactions to protein (by a trichloroacetic acid method) and phenol (by a ferric chloride method).