The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2002

Filed:

Sep. 20, 1999
Applicant:
Inventors:

Mark Fisher, London, GB;

Christopher John Taylorson, Ilford, GB;

Stuart Harbron, Berkhamsted, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C12Q 1/68 ; G01N 3/121 ; G01N 3/353 ; A61K 3/9395 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C12Q 1/68 ; G01N 3/121 ; G01N 3/353 ; A61K 3/9395 ;
Abstract

Probes comprise S1 and P1 nuclease (as an enzyme label) linked to a specific binding member such as a nucleotide sequence or an antibody. Such probes are useful for sandwich assays. As compared with known probes using alkaline phosphatase as a label, advantages include relative insensitivity to phosphate and elevated temperature and reduced risk of nonspecific binding.


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