The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2002
Filed:
Mar. 09, 2001
Tadashi Terasaka, Ikeda, JP;
Katsuya Nakamura, Takatsuki, JP;
Nobuo Seki, Takarazuka, JP;
Masako Kuno, Amagasaki, JP;
Susumu Tsujimoto, Fujiidera, JP;
Akihiro Sato, Kobe, JP;
Isao Nakanishi, Tenri, JP;
Takayoshi Kinoshita, Tsukuba, JP;
Nobuya Nishio, Yawara-mura, JP;
Hiroyuki Okumura, Osaka, JP;
Kiyoshi Tsuji, Kishiwada, JP;
Fujisawa Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
Imidazole compounds having adenosine deaminase inhibitory activity represented by formula (I) wherein R is hydrogen, hydroxy, protected hydroxy, or aryl optionally substituted with suitable substituent(s); R is hydrogen or lower alkyl; R is hydroxy or protected hydroxy; R is cyano, (hydroxy)iminoamino(lower)alkyl, carboxy, protected carboxy, heterocyclic group optionally substituted with amino, or carbamoyl optionally substituted with suitable substituent(s); and —A— is —Q— or —O—Q—, wherein Q is single bond or lower alkylene, provided that when R is lower alkyl, then R is hydroxy, protected hydroxy, or aryl optionally substituted with suitable substituent(s), its prodrug, or their salt. The compounds are useful for treating and/or preventing diseases for which adenosine is effective.