The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2002
Filed:
Aug. 23, 2000
Applicant:
Inventor:
Allan H. Conney, Princeton, NJ (US);
Assignee:
Rutgers, the State University, New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 3/500 ; A61K 3/156 ;
U.S. Cl.
CPC ...
A61P 3/500 ; A61K 3/156 ;
Abstract
Modified 2-alkoxyestradiol compounds wherein all hydrogens of the carbon next to the oxygen of the alkoxy moiety at position 2 are substituted with a halogen, alkyl or aromatic group, or a trifluoromethyl group are provided. Methods of using compositions containing these compounds to inhibit microtubule formation and tubulin polymerization or depolymerization in cells and to treat diseases characterized by abnormal cell mitosis are also provided.