The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2002

Filed:

Oct. 28, 1999
Applicant:
Inventors:

Masaaki Muramatsu, Tokyo, JP;

Takuji Shirasawa, Tokyo, JP;

Hiroshi Tokumitsu, Kagawa, JP;

Teruhisa Noguchi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/12 ;
U.S. Cl.
CPC ...
C12N 9/12 ;
Abstract

A mouse CDNA encoding a protein comprising a serine/threonine protein kinase region was isolated by effecting PCR using a synthetic DNA corresponding to the kinase-conserved region as a primer and a rat cDNA as a template. A mouse cDNA library was screened using the DNA fragment thus obtained as a probe. The multiple human and mouse cDNAs having the similar structure to the isolated mouse cDNA were successfully isolated based on the sequence of the isolated mouse cDNA. An antisense DNA against the isolated mouse cDNA was synthesized, and its effect on a nerve cell was studied to confirm that the antisense DNA inhibits axonal elongation.


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