Magnetic levitation stirring devices and machines for mixing in vessels

Abstract

The invention provides a simple method, devices and several machines for simultaneously stirring and aerating thousands of vessels or wells of microplates in a robust manner and with economy. This method uses the simple principle of magnetic stirrers being levitated vertically when passed laterally or vertically through a strong horizontal dipole magnetic field. The dipole magnetic fields may be produced by using permanent magnets, electromagnets or a modulating/reversing electro-magnetic field. Each vessel contains a magnetic ball, disc, bar, dowel or other shape (stirrers) which in their magnetic attraction to the dipole magnetic field will cause the stirrers to levitate up in the vessel as the stirrer's magnetic poles attempt to align with the center of the dipole's magnetic field. The stirrers will fall to the bottom of the vessel by gravity or by changing the relative position of the levitating magnetic field to pull them down, or by passing the vessel laterally over another magnetic field. The up and down movement of the stirrers provides a vigorous mixing of the contents of many vessels at same time. If the level of the vessel's meniscus is situated so the stirrers pass through it on their way up and down, the air/liquid interface is significantly increased thereby significantly increasing aeration of the liquid.