The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2002
Filed:
Aug. 02, 2000
Applicant:
Inventors:
Uwe Michelsen, Weinheim, DE;
Karl Holschuh, Seeheim-Jugenheim, DE;
Robertus Hendriks, Heidelberg, DE;
Assignee:
Merck Patent Gesellschaft, Darmstadt, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 2/100 ; C07H 2/102 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C07H 2/100 ; C07H 2/102 ; C07H 2/104 ;
Abstract
The invention provides a method for isolating and purifying nucleic acids from liquid samples. The method comprises using a solid carrier which is essentially made of oxide inorganic materials containing hydroxyl groups (e.g., silica gel or hydroxylapatite). The nucleic acids are bound to the carrier material in the acidic pH range while they are eluted in the alkaline pH range.