The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2002

Filed:

Jul. 21, 2000
Applicant:
Inventor:

Sumner H. Burstein, Framingham, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/135 ; A61K 3/144 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/135 ; A61K 3/144 ; C07D / ; C07D / ;
Abstract

The present invention relates to non-psychoactive derivatives of tetrahydro-cannabinol, which exhibit anti-inflammatory, analgesic and leukocyte antiadhesion activities. The invention includes novel derivatives of (3R,4R)-&Dgr; -tetrahydrocannabinol-11-oic acids [hereinafter referred to as (3R,4R)-&Dgr; -THC-11-oic acid], as well as pharmaceutical compositions containing the (3R,4R)-&Dgr; -THC-11-oic acid derivatives. The invention further covers methods of administering the novel derivatives and pharmaceutical compositions as therapeutic agents in the treatment of pain and tissue inflammation. Non-psychoactive derivatives of &Dgr; -THC-11-oic acid are described which have analgesic and anti-inflammatory properties.


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