The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2002

Filed:

Jun. 25, 1999
Applicant:
Inventors:

Prabhakara P. Reddi, Charlottesville, VA (US);

Charles J. Flickinger, Charlottesville, VA (US);

John C. Herr, Charlottesville, VA (US);

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C12N 1/563 ; C12N 5/00 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C12N 1/563 ; C12N 5/00 ;
Abstract

The present invention relates to compositions and methods for screening compounds that modulate meiotic progression. In particular, it relates to compositions comprising nucleotides from the mouse 5′ regulatory region, and transcriptionally active fragments thereof, that control the expression of a testis-enriched protein, SP-10. Specifically provided are expression vectors, host cells, and transgenic animals. The SP-10 promoter controls the expression of a heterologous gene, e.g., green fluorescent protein. The invention relates to methods for using the vectors, cells, and animals for screening candidate molecules for agonists and antagonists of sperm development and fertilization. Methods for using molecules and compounds identified by the screening assays for therapeutic treatments are provided.


Find Patent Forward Citations

Reddi, Prabhakara. (2002). Methods and compositions for modulating spermatogenesis (U.S. Patent No. 6355480). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6355480

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…