The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2002

Filed:

Nov. 13, 1999
Applicant:
Inventors:

Valery V. Novokhatny, Raleigh, NC (US);

Gary J. Jesmok, Richmond, CA (US);

Kyle A. Landskroner, Mill Valley, CA (US);

Kathryn K. Taylor, Apex, NC (US);

Thomas P. Zimmerman, Raleigh, NC (US);

Assignee:

Bayer Corporation, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/848 ; C12N 9/48 ; C12N 9/72 ; C12N 9/68 ;
U.S. Cl.
CPC ...
A61K 3/848 ; C12N 9/48 ; C12N 9/72 ; C12N 9/68 ;
Abstract

The invention provides an improved method of thrombolytic therapy by the direct admiistration of active plasmin to a clot site via catheter. An active, stable preparation of plasmin is provided, as is a process for activation and isolation of active plasmin.


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