The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2002
Filed:
Aug. 28, 1998
Applicant:
Inventors:
Marie Demay, Wellesley, MA (US);
Yan Chun Li, Chicago, IL (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 6/7027 ; A01K 6/700 ; G01N 3/300 ; C12N 5/00 ; C12N 1/500 ;
U.S. Cl.
CPC ...
A01K 6/7027 ; A01K 6/700 ; G01N 3/300 ; C12N 5/00 ; C12N 1/500 ;
Abstract
A transgenic mouse containing disruptions in both vitamin D alleles and lacking vitamin D receptor activity is described. The transgenic mouse displays perioral and periorbital alopecia, hypocalcemia, hypophosphatemia, and bone demineralization. The transgenic mouse is useful for screening treatments for a number of conditions associated with vitamin D receptor related disorders including skin disorders, immune system disorders, and proliferative disorders.