The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2002
Filed:
Dec. 17, 1991
Chromophore containing compounds and their use in determining interleukin-1&bgr; convertase activity
Applicant:
Inventors:
Kevin T. Chapman, Scotch Plains, NJ (US);
Malcolm Maccoss, Freehold, NJ (US);
Richard A. Mumford, Red Bank, NJ (US);
Nancy A. Thornberry, Westfield, NJ (US);
Jeffrey R. Weidner, Iselin, NJ (US);
William K. Hagmann, Westfield, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/804 ; A61K 3/806 ; A61K 3/800 ;
U.S. Cl.
CPC ...
A61K 3/804 ; A61K 3/806 ; A61K 3/800 ;
Abstract
Disclosed are novel chromophore containing compounds of Formula I and their use in determining interleukin-1&bgr; convertase (ICE) activity. ICE has been implicated in inflammatory or immune-based diseases of the lung and airways; central nervous system and surrounding membranes; the eyes and ears; joints, bones, and connective tissues; cardiovascular system including the pericardium; the gastrointestinal and urogenital systems; the skin and mucosal membranes.