The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2002

Filed:

Oct. 22, 1999
Applicant:
Inventors:

Andreas Plückthun, Zürich, CH;

Jozef Hanes, Hamburg, DE;

Lutz Jermutus, Zürich, CH;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/00 ; C07H 2/102 ; C07H 2/104 ; C12N 1/500 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/00 ; C07H 2/102 ; C07H 2/104 ; C12N 1/500 ;
Abstract

The present invention relates to methods for identifying nucleic acid molecules encoding (poly)peptides that interact with target molecules. The method of the present invention is particularly characterized by an in vitro translation step under conditions that allow formation of polysomes in the presence of antisense oligonucleotides complementary to the tag-coding sequence of ssrA-RNA. The present invention further relates to kits that are useful for carrying out the method of the invention.


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