The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2002

Filed:

Aug. 03, 1999
Applicant:
Inventors:

Simon Wright, Sheffield, GB;

Paul Heath, Sheffield, GB;

Paul Orange, Stockport, GB;

Ronald Carl Alan Pearson, Newcastle, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C07H 2/104 ; C12P 1/934 ; C12N 9/16 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C07H 2/104 ; C12P 1/934 ; C12N 9/16 ;
Abstract

A group of oligonucleotides for the identification of sequences in a sample comprising human histamine H receptor DNA, cDNA or RNA originating from a tissue sample or body fluid is employed in the diagnosis and/or treatment of human neurological and psychiatric disorders, particularly schizophrenia, and diseases of other systems or organs of the human body. The oligonucleotides, suitable for use as primers for the amplification of DNA corresponding to a region of a human histamine H receptor, have nucleotide sequences selected from: 5′ACACCAGCCTGGATGTGA 3′(as listed in SEQ ID NO:12), 5′TCACATCCAGGCTGGTCT 3′ (as listed in SEQ ID NO:13), 5′ CAATCATACCACCTCTAA 3′ (as listed in SEQ ID NO:14), 5′ ACACAAACGCGGTGAAGT 3′(as listed in SEQ ID NO:15). Also described is a diagnostic kit comprising one or more of the above mentioned oligonucleotides.


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