The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2002
Filed:
Feb. 21, 2001
Applicant:
Inventors:
Peter H. G. Wiegerinck, Arnhem, NL;
Duncan Sperling, Oss, NL;
Lesly Braamer, Zutphen, NL;
Eric W. P. Damen, Nijmegen, NL;
Johan W. Scheeren, Malden, NL;
Dick de Vos, Oegstgeest, NL;
Assignee:
Pharmachemie B.V., Haarlem, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K 3/1337 ;
U.S. Cl.
CPC ...
C07D / ; A61K 3/1337 ;
Abstract
The invention relates to water soluble antitumor analogs of paclitaxel of formula (I) wherein R =C(O)CH CH(OH)COOX, R =H, C(O)CH CH(OH)COOX, X=H, Li, Na or any other pharmaceutically acceptable counterion, as well as to a pharmaceutical composition comprising an antineoplastically effective amount of such analogs as an active ingredient.