The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2002
Filed:
Feb. 27, 2001
Applicant:
Inventors:
Stephan Lensky, Kürten, DE;
Bernd Riedl, Wuppertal, DE;
Chantal Fürstner, Mülheim an der Ruhr, DE;
Jens Ergüden, Wuppertal, DE;
Frank Böss, Wuppertal, DE;
Bernhard Schmidt, Lindlar, DE;
Franz-Josef van der Staay, Lohmar-Wahlscheid, DE;
Werner Schröder, Wuppertal, DE;
Joachim Schuhmacher, Wuppertal, DE;
Delf Schmidt, Wuppertal, DE;
Assignee:
Bayer Aktiengesellschaft, Leverkusen, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/142 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/142 ; C07D / ;
Abstract
The present invention relates to novel 2-aminocarbonyl-5(2H)-isoxazolones as selective ligands of a high-affinity binding site of diisopropyl fluorophosphate (DFP) on brain membranes for the prophylaxis and treatment of disorders of the central nervous system, in particular cognitive disorders, depression, schizophrenia and anxiety.