The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2002
Filed:
Jul. 29, 1999
Applicant:
Inventors:
Ross Rabin, Lafayette, CO (US);
Michael Lochrie, Louisville, CO (US);
Nebojsa Janjic, Boulder, CO (US);
Larry Gold, Boulder, CO (US);
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C07H 2/102 ; C12Q 1/68 ; C12P 1/934 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C07H 2/102 ; C12Q 1/68 ; C12P 1/934 ;
Abstract
The invention provides nucleic acid ligands to hepatocyte growth factor/scatter factor (HGF) and its receptor c-met. The nucleic acid ligands of the instant invention are isolated using the SELEX method. SELEX is an acronym for Systematic Evolution of Ligands by EXponential enrichment. The nucleic acid ligands of the invention are useful as diagnostic and therapeutic agents for diseases in which elevated HGF and c-met activity are causative factors.