The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2002
Filed:
Dec. 29, 2000
Applicant:
Inventors:
Robert Plourde, Jr., Richmond, VA (US);
Mark C. Sleevi, Midlothian, VA (US);
Rachel K. Longo, Mechanicsville, VA (US);
Assignee:
Insmed Pharmaceuticals, Inc., Richmond, VA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 3/514 ; C07C 3/508 ;
U.S. Cl.
CPC ...
C07C 3/514 ; C07C 3/508 ;
Abstract
The present invention relates to methods for the production and isolation of D-chiro-inositol (DCI) from kasugamycin. More specifically, the present invention relates to a method of producing DCI by hydrolysis of kasugamycin with aqueous trifluoroacetic acid in the presence of a strongly acidic ion exchange resin. The present invention further relates to methods of isolating DCI from an aqueous mixture, such as a hydrolysis mixture, either directly or by forming an organic derivative of DCI.