The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2002

Filed:

May. 25, 2000
Applicant:
Inventors:

Ugur Sahin, Homburg/Saar, DE;

Özlem Türeci, Homburg/Saar, DE;

Yao-Tseng Chen, New York, NY (US);

Lloyd J. Old, New York, NY (US);

Michael Pfreundschuh, Homburg/Saar, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; G01N 3/3574 ; C07K 1/4435 ;
U.S. Cl.
CPC ...
G01N 3/353 ; G01N 3/3574 ; C07K 1/4435 ;
Abstract

The invention relates to assays for determining breast cancer or melanoma. It has been found that the accuracy of such assays can be improved by assaying samples for three or more known tumor rejection antigen precursors. For breast cancer, the tumor rejection antigen precursors known as SCP-1, NY-ESO-1, and SSX-2 are assayed. For melanoma, SSX-2, NY-ESO-1, and MAGE-3 are assayed. Additional known tumor rejection antigen precursors can also be determined to confirm the assays. It is preferred to carry these out via polymerase chain reactions.


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