The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2002

Filed:

Apr. 02, 1999
Applicant:
Inventors:

Sabine M. Axt, Sunnyvale, CA (US);

Timothy J. Church, San Mateo, CA (US);

Witold Hruzewicz, Berkeley, CA (US);

John R. Jacobsen, San Francisco, CA (US);

Thomas E. Jenkins, La Honda, CA (US);

Yu-Hua Ji, San Mateo, CA (US);

J. Kevin Judice, Montara, CA (US);

Assignee:

Advanced Medicine, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K 3/1165 ;
U.S. Cl.
CPC ...
C07C / ; A61K 3/1165 ;
Abstract

Novel compounds, pharmaceutical compositions and methods are disclosed for producing local anesthesia of long-duration. The compounds of this invention are multibinding compounds that comprise from 2 to 10 ligands covalently attached to a linker or linkers, each ligand being capable of binding to a ligand binding site in a voltage-gated Na channel to modulate the biological processes/functions thereof.


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