The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2002
Filed:
Dec. 15, 1999
Applicant:
Inventors:
Michael R. Kozlowski, Palo Alto, CA (US);
Robert T. Lum, Palo Alto, CA (US);
Steven R. Schow, Redwood Shores, CA (US);
Hugo O. Villar, Newark, CA (US);
Micheal M. Wick, Woodside, CA (US);
Assignee:
Telik, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/147 ; A61K 3/1425 ;
U.S. Cl.
CPC ...
A61K 3/147 ; A61K 3/1425 ;
Abstract
Methods for treating diseases associated with the activity of the insulin growth factor-1 receptor (IGF-1R), such as cancer, are provided. Methods for inhibiting cell growth and proliferation, especially of tumor cells, and promoting apoptosis are also provided. Each of these methods employs the use of a heteroaryl-aryl urea compound as an antagonist for IGF-1R.