The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2002
Filed:
May. 07, 1999
Applicant:
Inventors:
Cayetano Gonzalez, Heidelberg, DE;
Bodo Lange, Heidelberg, DE;
Assignee:
The European Molecular Biology Laboratory, Heidelberg, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; G01N 3/353 ; C12P 2/106 ; B01D 5/944 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; G01N 3/353 ; C12P 2/106 ; B01D 5/944 ;
Abstract
The present invention is directed to methods for screening for fragments, derivatives and analogs of Hsp90 that are altered in their subcellular localization, and thus, altered in their activity as compared to wild type Hsp90. The present invention is also directed to screening for modulators of Hsp90 activity as determined by assaying for altered subcellular localization of Hsp90. The present invention is further directed to diagnostic, prognostic and screening uses of Hsp90/centrosome co-purification.