The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2001
Filed:
Jan. 19, 2000
Hiroyuki Koshio, Tsukuba, JP;
Fukushi Hirayama, Tsukuba, JP;
Tsukasa Ishihara, Tsukuba, JP;
Masashi Funatsu, Tsukuba, JP;
Tomihisa Kawasaki, Tsukuba, JP;
Yuzo Matsumoto, Tsukuba, JP;
Yamanouchi Pharmaceutical Co., Tokyo, JP;
Abstract
Hexahydro-1,4-diazepine derivatives represented by general formula (I); pharmaceutically acceptable salts thereof; and drugs containing the same as the active ingredient, such as activated blood coagulation factor X inhibitor, wherein A: phenylene, pyridylene, or the like; B: a 5- or 6-membered aryl or heteroaryl ring; X: —CO—, —CONH—, —CSNH—, —SO,—, —SO,NH—, or the like; Y: a bond or alkylene; R,: hydrogen, alkyl, —Y—(hetero) aryl, or the like; R,: hydrogen, alkoxy, —COOH, or the like; R,: amidino or a group capable of being converted into amidino; and R,, R,: each independently hydrogen or lower alkyl.