The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2001
Filed:
Apr. 19, 2000
Thomas Joseph Carr, Phoenixville, PA (US);
Renee Louise Desjarlais, St. Davids, PA (US);
Timothy Francis Gallagher, Harleysville, PA (US);
Stacie Marie Halbert, Harleysville, PA (US);
Hye-Ja Oh, Exton, PA (US);
Scott Kevin Thompson, Phoenixville, PA (US);
Daniel Frank Veber, Ambler, PA (US);
Dennis Shinji Yamashita, King of Prussia, PA (US);
Jack Hwekwo Yen, Malvern, PA (US);
SmithKline Beecham Corporation, Philadelphia, PA (US);
Abstract
The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting said bone loss or excessive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.