The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2001
Filed:
Apr. 30, 1999
C. Ron Wilson, Loveland, OH (US);
David L. Craft, Fort Thomas, KY (US);
L. Dudley Eirich, Cincinnati, OH (US);
Mark Eshoo, Fairfax, CA (US);
Krishna M. Madduri, Westfield, IN (US);
Cathy A. Cornett, Crescent Springs, KY (US);
Alfred A. Brenner, Santa Rosa, CA (US);
Maria Tang, Fairfield, CA (US);
John C. Loper, Cincinnati, OH (US);
Martin Gleeson, San Diego, CA (US);
Other;
Abstract
Novel genes have been isolated which encode cytochrome P450 and NADPH reductase enzymes of the &ohgr;-hydroxylase complex of,20336. Vectors including these genes, transfected host cells and transformed host cells are provided. Methods of producing of cytochrome P450 and NADPH reductase enzymes are also provided which involve transforming a host cell with a gene encoding these enzymes and culturing the cells. Methods of increasing the production of a dicarboxylic acid and methods of increasing production of the aforementioned enzymes are also provided which involve increasing in the host cell the number of genes encoding these enzymes. A method for discriminating members of a gene family by quantifying the expression of genes is also provided.