The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2001
Filed:
May. 12, 1998
Bernd Klinksiek, Bergisch Gladbach, DE;
Said Mahiout, Bergisch Gladbach, DE;
Ricarda-Christine Nothelle, Leverkusen, DE;
Hans-Jürgen Hamann, Dormagen, DE;
Jürgen Sdebik, Düsseldorf, DE;
Bayer Aktiengesellschaft, Leverkusen, DE;
Abstract
In the procedure for the production of a formulation of parenterally administrable pharmaceutical preparations, a liposome dispersion is used as a carrier for a pharmaceutical active compound. For the preparation of the liposome dispersion, an aqueous predispersion of one or more amphiphilic substances is fed to a high-pressure homogenizer in which the predispersion is pumped under a pressure from 600 bar to 900 bar through a homogenizer nozzle (,) having a diameter of 0.1 to 0.5 mm. The homogenizer nozzle has an inlet channel (,) and an outlet channel (,) and consists of a hard ceramic plate (,), in which the bore (,) is present, pressed into a steel body (,). The inlet channel (,) and the outlet channel (,) are likewise incorporated into the steel body (,).