The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2001
Filed:
Nov. 08, 1999
Applicant:
Inventors:
Ronald G. Crystal, Potomac, MD (US);
Todd K. Rosengart, Highland Park, IL (US);
Assignee:
Cornell Research Foundation, Inc., Ithaca, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 4/800 ; A61K 3/800 ; C12N 1/563 ; C12N 1/586 ; C07K 1/00 ;
U.S. Cl.
CPC ...
A61K 4/800 ; A61K 3/800 ; C12N 1/563 ; C12N 1/586 ; C07K 1/00 ;
Abstract
The present invention provides a method for enhancing the level of perfusion of blood to a target location in a host comprising establishing a gradient of an angiogenic mediator of increasing concentration from a source location (e.g., an angiogenically functional location) in the host to a target location (e.g., an angiogenically dysfunctional location) in the host, such that the level of perfusion of blood to the target location in the host is enhanced.