The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2001

Filed:

Dec. 16, 1997
Applicant:
Inventors:

Klasu Muhlegger, Polling, DE;

Herbert Von Der Eltz, Weilheim, DE;

Frank Seela, Osnabruck, DE;

Helmut Rosemeyer, Osnabruck, DE;

Assignee:

Roche Diagnostics GmbH, Mannheim, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 4/304 ; A61K 3/170 ;
U.S. Cl.
CPC ...
A01N 4/304 ; A61K 3/170 ;
Abstract

Oligodeoxyribonucleotides in which at least two 2′-deoxy-&bgr;-D-erythro-pentofuranosyl groups are replaced by 2′-deoxy-&bgr;-D-threo-pentofuranosyl groups at both the 5′ end and 3′ end, and oligodeoxyribonucleotides in which at least 20% of the 2′-deoxy-&bgr;-D-erythro-pentofuranosyl groups in consecutive nucleotide building blocks are replaced by 2′-deoxy-&bgr;-D-threo-pentofuranosyl groups and which are composed of 6 to 100 nucleotide building blocks, are suitable for the inhibition of the expression of viral genes and oncogenes by the antisense principle and can be used for the production of pharmaceutical agents with antiviral activity.


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