The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2001
Filed:
Sep. 15, 1997
Applicant:
Inventor:
Luuk Hilgers, Utrecht, NL;
Assignee:
American Cyanamid Company, Madison, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; A61K 4/736 ; A61K 4/740 ; A61K 4/744 ;
U.S. Cl.
CPC ...
A61K 3/900 ; A61K 4/736 ; A61K 4/740 ; A61K 4/744 ;
Abstract
Vaccine adjuvants comprising a sulpholipid polysaccharide in combination with an interface-forming constituent. The invention also provides a method for preparing a vaccine by emulsifying an aqueous solution of an antigen and a sulpholipid polysaccharide. The adjuvants are stable at high temperatures, and are at least as effective as conventional adjuvants. Their local toxicity, i.e. their reactogenicity, is generally lower than that of conventional adjuvants.