The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2001
Filed:
Jan. 25, 2000
Applicant:
Inventors:
Ursula Grohman, Perugia, IT;
Jacques Van Snick, Brussels, BE;
Assignee:
Ludwig Institute For Cancer Research, , NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A16K 4/500 ; A16K 3/800 ;
U.S. Cl.
CPC ...
A16K 4/500 ; A16K 3/800 ;
Abstract
The invention involves the recognition of IL-9 as a molecule involved in induction of IL-10. Administration of IL-9 leads to protection against conditions where IL-10 production is warranted, such as infections by Gram negative bacteria. Examples of such conditions are septic shock and endotoxemia. Also a part of the invention are methods of treatment where IL-9 and a phosphodiesterase inhibitor are administered to a subject. Compositions, such as kits which include these two components are a part of the invention, as is treatment of conditions involving excess IL-10 production by administering an IL-9 inhibitor.