The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2001

Filed:

Jan. 22, 2001
Applicant:
Inventors:

Jill E. Parker, Floresville, TX (US);

Johnathan L. Kiel, Universal City, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/08 ;
U.S. Cl.
CPC ...
C12N 5/08 ;
Abstract

The cell line HeLa is transformed with the chromosomal insertion of the plasmid pSV,neoNR10,, ATCC No. 69617. The transformed cells, HeLaNR1, produce diazoluminomelanin (DALM) intra cellularly when provided with nitrate, luminol and 3-amino-L-tyrosine•HC1 (3AT). The modified cells can be used to study mechanisms for radiofrequency and light radiation interactions with carcinoma of the cervix. The effects of drugs, hormones, and cytokines that affect the expression of nitric oxide synthase and its activity can also be studied to understand the effects of these materials on cervix cells.


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