The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2001
Filed:
Nov. 29, 1995
Applicant:
Inventors:
Haruya Sato, Chiba-ken, JP;
Keiji Yamamoto, Chiba-ken, JP;
Kokichi Suzuki, Chiba-ken, JP;
Masahiro Ikeda, Tokyo, JP;
Masahiro Sakagami, Chiba-ken, JP;
Makoto Taniguchi, Saitama-ken, JP;
Assignee:
Drug Delivery System Institute, Ltd., Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; C07K 1/107 ; C07K 1/12 ; C12P 1/300 ;
U.S. Cl.
CPC ...
C07C / ; C07K 1/107 ; C07K 1/12 ; C12P 1/300 ;
Abstract
Transglutaminase is allowed to act upon both a physiologically active protein (inclusive of a fused protein thereof with a peptide through acid amide bonding) and an amino group donor containing the polyethylene glycol, polysaccharide, polyamino acid or branched type sugar derivative moiety, whereby the physiologically active protein is modified without spoiling its inherent physiological activities, and may be improved in its qualification as a drug.