The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2001

Filed:

Oct. 15, 1998
Applicant:
Inventors:

Robert M. Bernard, Rancho Santa Fe, CA (US);

Andrew W. Hannaman, San Diego, CA (US);

Silvia Sfiligoi, Del Mar, CA (US);

Assignee:

Ichor Medical Systems, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1355 ; A61K 3/156 ; A61K 3/1573 ; A61K 3/808 ; A61N 1/30 ;
U.S. Cl.
CPC ...
A61K 3/1355 ; A61K 3/156 ; A61K 3/1573 ; A61K 3/808 ; A61N 1/30 ;
Abstract

Methods for improving the efficiency of electroporation protocols as well as methods to enhance the permeabilized state, in order to improve the intracellular delivery of therapeutic substances, involve the use of at least one agent which is capable of prolonging the permeability of the cell membranes in the tissue exposed to an electroporation-inducing electrical field.


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