The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2001
Filed:
May. 18, 2000
Applicant:
Inventor:
Peter Loeliger, Muttenz, CH;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 4/354 ; A61K 9/08 ; A61K 3/1513 ; A61K 4/718 ;
U.S. Cl.
CPC ...
A01N 4/354 ; A61K 9/08 ; A61K 3/1513 ; A61K 4/718 ;
Abstract
Difficulties in preparing a stable pharmaceutical composition containing 5-Isopropyl-pyridine-2-sulfonic acid 6-(2-hydroxy-ethoxy)-5(2-methoxy-phenoxy)2-(2-1H-tetrazol-5-yl-pyridin-4yl)-pyrimidin-4-ylamide in form of the water soluble disodium salt, a buffer and preferably a metal complex forming agent, have been encountered. It was unexpectedly found that these difficulties can be overcome by adjusting the pH of the solution with an acid to over and above 8,2, preferably to 9,0, but not higher than 10.