The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2001
Filed:
Sep. 26, 2000
Sergio Mantegani, Milan, IT;
Gabriella Traquandi, Milan, IT;
Tiziano Bandiera, Gamboló Pavia, IT;
Jacqueline Lansen, Milan, IT;
Mario Varasi, Milan, IT;
Pharmacia & Upjohn S.p.A., Milan, IT;
Abstract
A compound of formula (1) wherein R,is hydrogen, hydroxy, a group of formula OR,wherein R,is C,-C,alkyl, C,-C,alkenyl or C,-C,cycloalkyl, halogen, amino which may be unsubstituted or mono or disubstituted by C,-C,alkyl, C,-C,alkenyl, aralkyl, acyl or trifluoroacetyl; R,is hydrogen, hydroxy, a group NR,R,wherein R,and R,independently represent hydrogen, an optionally substituted C,-C,alkyl, C,-C,alkenyl, C,-C,cycloalkyl or, taken together with the nitrogen atom, represent an optionally substituted C,-C,heterocyclic ring; R,is hydrogen, hydroxy, R,is a 2-substituted thiazolyl or imidazolyl system and the pharmaceutically acceptable salt thereof, is useful in the treatment of amyloidosis. Processes for the preparation and pharmaceutical compositions are also described.